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#5 · fastest growing

Zyphra

Open superintelligence lab + Zyphra Cloud running entirely on AMD hardware.

AI Research / CloudPalo Alto / SF
Multimodal foundation models (ZAYA / Maia agent) and cloud inference/training stack optimized for AMD Instinct GPUs.
Series A / growth
Series A at $1B valuation; rumored $500M raise with AMD participation targeting ≥$5B

Notable

  • Trains and serves on AMD (not Nvidia-default)
  • IBM Cloud partnership for large MI300X cluster
  • Positioned as US open-weight alternative with strong cloud story

Links

Map

Approximate HQ location (SF / Bay Area cluster).

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